Downtown San Francisco Vacations from $372
Book a Hotel + Flight or Car together to unlock savings
Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Stanford Court San Francisco
Downtown San Francisco
Price was $855, price is now $401 per person
$401
per person
Jan 20 - Jan 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9/10 Wonderful! (1,793 reviews)
Staff was very welcoming and hospitable. Great location!
Reviewed on Nov 12, 2026
The Grove Inn
Western Addition
Price was $708, price is now $425 per person
$425
per person
Jan 15 - Jan 18
found 12 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.2/10 Wonderful! (747 reviews)
This inn was great! Peaceful and cozy rooms with nice amenities. My husband and I enjoyed our stay here!
Reviewed on Nov 12, 2026
Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Nov 29 to Nov 30
$140 total
Nov 29 - Nov 30
Total with taxes and fees
9/10 Wonderful! (6,488 reviews)
"Great"
Reviewed on Nov 12, 2026
Hilton San Francisco Union Square
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $188 total per night from Nov 26 to Nov 27
$188 total
Nov 26 - Nov 27
Total with taxes and fees
FOUND Hotel Carlton, Nob Hill
1075 Sutter St San Francisco CA
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $93 total per night from Dec 14 to Dec 15
$93 total
Dec 14 - Dec 15
Total with taxes and fees
8.6/10 Excellent! (2,050 reviews)
"Excelente hospedaje. Ubicación estratégica en mi viaje a San Francisco!! Fácil acceso a transporte público. Zona segura y silenciosa . Habitaciones espaciosas , limpias , con todo lo necesario y cómodas sin duda , Olvera dmd y"
Reviewed on Nov 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Downtown San Francisco attractions
Things to do
Alcatraz Inside tour with Round trip ferry & Audio App Packages
$86
per adult
94% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
Explore a world of travel with Expedia
- Alamo Square
- Yerba Buena Ice Skating Center
- Golden Gate Theatre
- Commercial Street
- Tin How Temple
- De Young Museum
- Shn Curran Theatre
- Greek Theater
- Coit Tower
- Sf Masonic Auditorium
- Bill Graham Civic Auditorium
- Japanese Tea Garden
- National Shrine of Saint Francis of Assisi
- Jack Kerouac Alley
- Union Square Ice Rink
- Civic Center Plaza
- Crocker Bank Building
- Dragon's Gate
- San Francisco Federal Building
- Conservatory of Flowers
- 555 California Street
- Van Ness Avenue
- San Francisco Mint
- Ghirardelli Chocolate Experience
- Civic Center Vacations
- Aquarium of the Bay
- American Conservatory Theater
- Saints Peter and Paul Church
- Uss Pampanito
- Chinese Historical Society of America
- San Francisco Zoo
- The Regency Ballroom
- Yerba Buena Gardens
- Lombard Street
- Grace Cathedral
- Telephone Pioneers Communication Museum
- Golden Gate Bridge
- Old St. Mary's Cathedral
- San Francisco Museum of Modern Art
- Alcatraz Island
- Kong Chow Temple
- Museum of Craft and Folk Art
- Cable Car Museum
- Balmy Alley
- Crocker Galleria
- San Francisco Vacations
- Sf Playhouse
- Musée Mécanique
- Children's Creativity Museum
- Columbus Tower
- Palace Hotel
- Oracle Park
- Walter S. Johnson Park
- Chase Center
- Moscone Convention Center
- San Francisco Maritime National Historical Park
- Palace of Fine Arts
- Maxwell Galleries
- Sf Armory
- Westfield San Francisco Centre
- Academy of Art University
- Mission San Francisco de Asís
- 450 Sutter Building
- Transamerica Redwood Forest
- Orpheum Theatre
- One Montgomery Terrace
- Muir Woods National Monument
- Chinatown Vacations
- Yerba Buena Center for the Arts
- Full House House
- Eleonore Austerer Gallery
- Transamerica Pyramid
- Ferry Building
- Crissy Field
- San Francisco City Hall
- Mrs. Doubtfire House
- Fisherman's Wharf Vacations
- St. Mary Square
- Union Square
- Union Square Vacations
- Wells Fargo History Museum
- United Nations Plaza
- Warfield Theatre
- Magowan's Infinite Mirror Maze
- Asian Art Museum of San Francisco
- Maiden Lane
- Pier 39
- Marines Memorial Theater
- The Cannery at Del Monte Square
- Lotta's Fountain
- Baker Beach
- Pacific-Union Club
- California Academy of Sciences
- Embarcadero Center
- Ripley's Believe It Or Not Museum
- Walt Disney Family Museum
- Ghirardelli Square
- St. Patrick Catholic Church
- Westin St Francis Hotel Glass Elevators
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.